Ozone therapy as adjuvant to the treatment of osteoradionecrosis. Case report

Francisco Ubiratan Ferreira de Campos, Carlos Goes Nogales, Paulo de Camargo Moraes, Rogério Heladio Motta, Juliana Cama Ramacciato


Ozone therapy has been shown to be an effective adjunctive therapeutic tool in the treatment of osteoradionecrosis acting directly on the repair. Thus, the objective of this case report was to present the benefits of using ozone therapy as an adjuvant to the treatment of osteoradionecrosis. Female patient, 57 years old, melanoderma, attended the Faculty of São Leopoldo Mandic reporting severe pain throughout her face with difficulty in eating, speaking and a bad taste in her mouth. In the intraoral examination an area of necrosis was found in the region of tooth 38, three months after extraction and 10 years after radiotherapy. Initially, the area was cleaned irrigated with saline and antibiotic therapy associated with 10% hydrogen peroxide as a mouthwash. Then the patient was referred to Ozone therapy Specialized Clinic. Appointments were made fortnightly. The lesion was washed with 250 ml of sterile ozonized bidistilled water at 8 µg/ml and the injection of 20 ml of the oxygen/ozone gas mixture at a concentration of 20 µg/ml, which was bubbled into the lesion through the presence of purulent drainage. Additionally, injections of 1 ml of gaseous ozone were made at 5 points around the lesion. To conclude the ozone therapy protocol ozonized oil was applied into the cavity. After 30 sessions the healed area was observed with no pain. Three-years follow up is displayed. Thus, it was concluded that ozone therapy improved the repair and controlled symptomatology

Palabras clave

Ozone therapy. Ozonated water. Ozonated oil. Osteoradionecrosis. Healing

Texto completo: PDF


  • No hay Refbacks actualmente.